OpenAI on NVIDIA Blackwell

Can I run gpt-oss 120B-A5.1B on an RTX 5080?

Not at Q4_K_M — it needs 67.4 GB against 14.2 GB available. You would need 5 of these cards.

Won't fit

67.4 GB of 14.2 GB · 473%
070 GB
Weights 66.0 GB
KV cache 0.6 GB
Runtime overhead 0.8 GB
Over the limit 53.2 GB

Short by 53.2 GB. You can run it with 7 of 36 layers on the RTX 5080 and the rest in system RAM, at roughly 15.9 tok/s — usable for batch work, painful for chat. A smaller quantisation or a shorter context is usually the better trade.

Generation15.9tok/s
Prompt processing4612tok/s
Max context0tokens
KV per 1K tokens0GB

Every quantisation of gpt-oss 120B-A5.1B on a RTX 5080

Highlighted row is the highest quality that still fits at 8K context.

QuantisationbpwWeights TotalVerdictMax ctxtok/s
FP16 / BF16 16.00 217.6 GB 218.9 GB Won't fit 4.52
INT8 / W8A8 8.50 115.3 GB 116.7 GB Won't fit 8.72
FP8 (E4M3) 8.00 108.8 GB 110.1 GB Won't fit 9.21
Q6_K 6.56 89.2 GB 90.6 GB Won't fit 11.4
Q5_K_M 5.67 77.1 GB 78.5 GB Won't fit 13.4
Q5_K_S 5.52 75.1 GB 76.4 GB Won't fit 13.7
Q4_K_M 4.85 66.0 GB 67.4 GB Won't fit 15.9
Q4_K_S 4.58 62.4 GB 63.8 GB Won't fit 16.7
Q4_0 4.55 62.0 GB 63.4 GB Won't fit 16.8
AWQ 4-bit 4.25 59.4 GB 60.7 GB Won't fit 17.4
GPTQ 4-bit 4.25 59.4 GB 60.7 GB Won't fit 17.4
MXFP4 4.25 59.4 GB 60.7 GB Won't fit 17.4
IQ4_XS 4.25 58.0 GB 59.3 GB Won't fit 17.8
Q3_K_M 3.91 53.4 GB 54.7 GB Won't fit 19.7
IQ3_M 3.70 50.6 GB 51.9 GB Won't fit 21.3
IQ3_XXS 3.06 41.9 GB 43.3 GB Won't fit 26.7
Q2_K 2.63 36.1 GB 37.5 GB Won't fit 31.2
IQ2_XXS 2.06 28.5 GB 29.8 GB Won't fit 43.8
IQ1_M 1.75 24.3 GB 25.7 GB Won't fit 56.0

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